Endocrine System

{"ops":[{"insert":"Diagnosis and reasoning"},{"insert":"\n","attributes":{"header":1}},{"insert":"This 10-year-old child has a history of inadequate weight gain and short stature, as per her mother.\n\nThe first step in such a case is to measure the patient\u0027s body parameters and plot them on the relevant growth curves. These are below the 3rd percentile for her age and gender, indicating true growth failure. Additionally, the weight-for-height ratio is between the 25th and 50th centile, further supporting this diagnosis.\n\nThe next step is determination of the appropriate proportions. The upper-to-lower body ratio in this case suggests proportional short stature, excluding skeletal dysplasias such as achondroplasia and osteogenesis imperfecta. A normal skeletal survey supports these findings.\n\nNote also that our patient\u0027s growth velocity is below the expected range for her age and her height is less than the calculated mid-parental height, ruling out familial or constitutional short stature.\n\nA thorough medical history and physical examination help assess for chronic diseases, recurre"}]}

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