Hyperactive

Endocrine System


Step 1: View Clinicals

{"ops":[{"insert":"A 49-year-old woman presents with progressive enlargement of the base of her neck.\n\nClose questioning reveals a history of palpitations, easy fatigability, insomnia, tremors, and excessive sweating for two months, along with a five-kilogram weight loss during the same period. Her husband also mentions that she prefers to keep the temperature at home on the lower side.\n\nShe has refused to seek medical advice thus far. However, being a professional singer, she is now worried about the possible repercussions on her voice.\n\nShe was diagnosed with type 2 diabetes mellitus three years ago, which is well controlled on metformin alone. Her surgical and gynecological histories are unremarkable, with her menopause occurring two years ago.\n\nHer random blood sugar and HbA1c are respectively 134 mg\/dL (target: \u003C180 mg\/dL) and 6.0% (target: \u003C7.0%). Serum electrolytes and a renal profile are both within normal parameters.\n\nA 12-lead ECG reveals a sinus tachycardia of 100 bpm, with no other rate, rhythm, or morphological abnormalities.\n"},{"insert":"\n"},{"insert":{"image":"\/storage\/case-images\/pd\/PD-M-243_en.png"}},{"insert":"\n"}]}

Step 2: Order Relevant Investigations

1. Thyroid function tests
2. Ultrasound thyroid
3. Serum TRAb levels
4. Thyroid radioisotope scan

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