Bruised

Blood & Lymphoreticular System


{"ops":[{"insert":"Diagnosis and reasoning"},{"insert":"\n","attributes":{"header":1}},{"insert":"This middle aged lady has presented with an ominous collection of symptoms: upper abdominal pain, extensive weight loss, new-onset easy bruising, and constitutional symptoms, all of which developed within a period of 3 weeks.\n\nHer examination is even more alarming, revealing the presence of pallor, generalized lymphadenopathy, and hepatosplenomagaly.\n\nNote that the above collection of clinical findings is strongly suggestive of a hematological malignancy; key concerns include lymphoma, chronic leukemia, and multiple myeloma and other monoclonal gammopathies.\n\nA complete blood count and peripheral smear are essential first-line investigations; the former reveals the presence of anemia and thrombocytopenia, with a lymphocyte predominant leukocytosis; the latter shows rouleaux formation with atypical lymphocytes and plasmacytoid cells.\n\nNote that the above findings allow us to considerably narrow down the possibilities, with Non-Hodgkin\u0027s Lymphoma (NHL), chronic lymphocytic leukemia (CLL"}]}

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