Legionnaires' Disease

Immune System


Clinicals - History

Fact Explanation
{"ops":[{"insert":"Introduction"},{"insert":"\n"}]}
{"ops":[{"insert":"Legionnaires\u0027 disease (LD), often referred to as legionellosis, is an infection caused by Legionella spp, most commonly L. pneumophila. These are gram-negative, aerobic, facultative intracellular bacilli found as free-living forms in freshwater and soil, or as intracellular parasites within protozoa."}]}
{"ops":[{"insert":"Symptoms of pneumonia"},{"insert":"\n"}]}
{"ops":[{"insert":"These include fever, nonproductive cough, headache, myalgias, rigors, dyspnea, diarrhea, and delirium. Importantly, these findings are nonspecific, being shared with patients having other types of pneumonia."}]}
{"ops":[{"insert":"Gastrointestinal symptoms"},{"insert":"\n"}]}
{"ops":[{"insert":"Between one-third to one-half of patients develop prominent gastrointestinal symptoms, including nausea, vomiting, and diarrhea."}]}
{"ops":[{"insert":"Environmental exposure"},{"insert":"\n"}]}
{"ops":[{"insert":"Legionella infection commonly occurs through exposure to contaminated water or soil following aerosolization of water particles containing the bacterium.\n\nPatients may have a history of exposure to water, such as may occur in periods of increased rainfall; or may work in a garden, for example. Alternately, the source may be a contaminated water supply or cooling system; these can be located in hotels, cruise ships, etc., leading to outbreaks of the disease."}]}
{"ops":[{"insert":"Risk factors"},{"insert":"\n"}]}
{"ops":[{"insert":"Patients who smoke, suffer from lung disease, are diabetic or have other immunocompromising conditions are at increased risk. Studies also show that males over 55 have a higher chance of developing LD."}]}
{"ops":[{"insert":"Introduction"},{"insert":"\n"}]}
{"ops":[{"insert":"Legionnaires\u0027 disease (LD), often referred to as legionellosis, is an infection caused by Legionella spp, most commonly L. pneumophila. These are gram-negative, aerobic, facultative intracellular bacilli found as free-living forms in freshwater and soil, or as intracellular parasites within protozoa."}]}
{"ops":[{"insert":"Symptoms of pneumonia"},{"insert":"\n"}]}
{"ops":[{"insert":"These include fever, nonproductive cough, headache, myalgias, rigors, dyspnea, diarrhea, and delirium. Importantly, these findings are nonspecific, being shared with patients having other types of pneumonia."}]}
{"ops":[{"insert":"Gastrointestinal symptoms"},{"insert":"\n"}]}
{"ops":[{"insert":"Between one-third to one-half of patients develop prominent gastrointestinal symptoms, including nausea, vomiting, and diarrhea."}]}
{"ops":[{"insert":"Environmental exposure"},{"insert":"\n"}]}
{"ops":[{"insert":"Legionella infection commonly occurs through exposure to contaminated water or soil following aerosolization of water particles containing the bacterium.\n\nPatients may have a history of exposure to water, such as may occur in periods of increased rainfall; or may work in a garden, for example. Alternately, the source may be a contaminated water supply or cooling system; these can be located in hotels, cruise ships, etc., leading to outbreaks of the disease."}]}
{"ops":[{"insert":"Risk factors"},{"insert":"\n"}]}
{"ops":[{"insert":"Patients who smoke, suffer from lung disease, are diabetic or have other immunocompromising conditions are at increased risk. Studies also show that males over 55 have a higher chance of developing LD."}]}

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